Interleukin-7 Influences FOXP3+CD4+ Regulatory T Cells Peripheral Homeostasis

Mechanisms governing peripheral CD4+ FOXP3+ regulatory T cells (Treg) survival and homeostasis are multiple suggesting tight and complex regulation of regulatory T cells homeostasis. Some specific factors, such as TGF-β, interleukin-2 (IL-2) and B7 costimulatory molecules have been identified as ess...

Full description

Bibliographic Details
Main Authors: Simonetta, Federico, Gestermann, Nicolas, Martinet, Kim Zita, Boniotto, Michele, Tissières, Pierre, Seddon, Benedict, Bourgeois, Christine
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346843/