4-(4-Amino-2-fluorophenoxy)-7-methoxyquinazolin-6-ol methanol monosolvate
In the title compound, C15H12FN3O3·CH3OH, the dihedral angle between the quinazoline ring system and the benzene ring is 81.18 (9)°. In the crystal, molecules are linked by N—H⋯O and O—H⋯N hydrogen bonds, generating [10-1] chains of alternating main molecules and solvent molecules. Weak C—H⋯O int...
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| Format: | Online |
| Language: | English |
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International Union of Crystallography
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344092/ |
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pubmed-3344092 |
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pubmed-33440922012-05-17 4-(4-Amino-2-fluorophenoxy)-7-methoxyquinazolin-6-ol methanol monosolvate Huang, Wei Tan, Aimin Organic Papers In the title compound, C15H12FN3O3·CH3OH, the dihedral angle between the quinazoline ring system and the benzene ring is 81.18 (9)°. In the crystal, molecules are linked by N—H⋯O and O—H⋯N hydrogen bonds, generating [10-1] chains of alternating main molecules and solvent molecules. Weak C—H⋯O interactions are also observed. International Union of Crystallography 2012-03-24 /pmc/articles/PMC3344092/ /pubmed/22606095 http://dx.doi.org/10.1107/S1600536812011725 Text en © Huang and Tan 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Huang, Wei Tan, Aimin |
| spellingShingle |
Huang, Wei Tan, Aimin 4-(4-Amino-2-fluorophenoxy)-7-methoxyquinazolin-6-ol methanol monosolvate |
| author_facet |
Huang, Wei Tan, Aimin |
| author_sort |
Huang, Wei |
| title |
4-(4-Amino-2-fluorophenoxy)-7-methoxyquinazolin-6-ol methanol monosolvate |
| title_short |
4-(4-Amino-2-fluorophenoxy)-7-methoxyquinazolin-6-ol methanol monosolvate |
| title_full |
4-(4-Amino-2-fluorophenoxy)-7-methoxyquinazolin-6-ol methanol monosolvate |
| title_fullStr |
4-(4-Amino-2-fluorophenoxy)-7-methoxyquinazolin-6-ol methanol monosolvate |
| title_full_unstemmed |
4-(4-Amino-2-fluorophenoxy)-7-methoxyquinazolin-6-ol methanol monosolvate |
| title_sort |
4-(4-amino-2-fluorophenoxy)-7-methoxyquinazolin-6-ol methanol monosolvate |
| description |
In the title compound, C15H12FN3O3·CH3OH, the dihedral angle between the quinazoline ring system and the benzene ring is 81.18 (9)°. In the crystal, molecules are linked by N—H⋯O and O—H⋯N hydrogen bonds, generating [10-1] chains of alternating main molecules and solvent molecules. Weak C—H⋯O interactions are also observed. |
| publisher |
International Union of Crystallography |
| publishDate |
2012 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344092/ |
| _version_ |
1611527175210532864 |