Deletion of scavenger receptor A protects mice from progressive nephropathy independent of lipid control during diet-induced hyperlipidemia

Scavenger receptor A (SR-A) is a key transmembrane receptor in the endocytosis of lipids and contributes to the pathogenesis of atherosclerosis. To assess its role in hyperlipidemic chronic kidney disease, wild-type and SR-A-deficient (knockout) mice underwent uninephrectomy followed by either norma...

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Bibliographic Details
Main Authors: Wang, Wenjian, He, Bin, Shi, Wei, Liang, Xinling, Ma, Jianchao, Shan, Zhixin, Hu, Zhaoyong, Danesh, Farhad R
Format: Online
Language:English
Published: Nature Publishing Group 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343314/