Tumor-promoting functions of transforming growth factor-β in progression of cancer

Transforming growth factor-β (TGF-β) elicits both tumor-suppressive and tumor-promoting functions during cancer progression. Here, we describe the tumor-promoting functions of TGF-β and how these functions play a role in cancer progression. Normal epithelial cells undergo epithelial-mesenchymal tran...

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Bibliographic Details
Main Authors: Miyazono, Kohei, Ehata, Shogo, Koinuma, Daizo
Format: Online
Language:English
Published: Informa Healthcare 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339546/