Intra-Aortic Clusters Undergo Endothelial to Hematopoietic Phenotypic Transition during Early Embryogenesis

Intra-aortic clusters (IACs) attach to floor of large arteries and are considered to have recently acquired hematopoietic stem cell (HSC)-potential in vertebrate early mid-gestation embryos. The formation and function of IACs is poorly understood. To address this issue, IACs were characterized by im...

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Bibliographic Details
Main Authors: Mizuochi, Chiyo, Fraser, Stuart T., Biasch, Katia, Horio, Yuka, Kikushige, Yoshikane, Tani, Kenzaburo, Akashi, Koichi, Tavian, Manuela, Sugiyama, Daisuke
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338791/