A Stochastic Markov Chain Model to Describe Lung Cancer Growth and Metastasis

A stochastic Markov chain model for metastatic progression is developed for primary lung cancer based on a network construction of metastatic sites with dynamics modeled as an ensemble of random walkers on the network. We calculate a transition matrix, with entries (transition probabilities) interpr...

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Bibliographic Details
Main Authors: Newton, Paul K., Mason, Jeremy, Bethel, Kelly, Bazhenova, Lyudmila A., Nieva, Jorge, Kuhn, Peter
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338733/