In Vitro RNase and Nucleic Acid Binding Activities Implicate Coilin in U snRNA Processing
Coilin is known as the marker protein for Cajal bodies (CBs), subnuclear domains important for the biogenesis of small nuclear ribonucleoproteins (snRNPs) which function in pre-mRNA splicing. CBs associate non-randomly with U1 and U2 gene loci, which produce the small nuclear RNA (snRNA) component o...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Public Library of Science
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338655/ |