Homocysteine, methylenetetrahydrofolate reductase C677T polymorphism and cognitive impairment: the health in men study

High total plasma homocysteine (tHcy) has been associated with cognitive impairment in later life, but it is unclear if this association is causal or is due to confounding. The C677T polymorphism of the 5,10 methylenetetrahydrofolate reductase gene (MTHFR) increases basal tHcy, but its contribution...

Full description

Bibliographic Details
Main Authors: Ford, A H, Flicker, L, Hankey, G J, Norman, P, van Bockxmeer, F M, Almeida, O P
Format: Online
Language:English
Published: Nature Publishing Group 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335075/