TRF2 Controls Telomeric Nucleosome Organization in a Cell Cycle Phase-Dependent Manner
Mammalian telomeres stabilize chromosome ends as a result of their assembly into a peculiar form of chromatin comprising a complex of non-histone proteins named shelterin. TRF2, one of the shelterin components, binds to the duplex part of telomeric DNA and is essential to fold the telomeric chromati...
Main Authors: | , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335031/ |