Systems Analysis of MVA-C Induced Immune Response Reveals Its Significance as a Vaccine Candidate against HIV/AIDS of Clade C

Based on the partial efficacy of the HIV/AIDS Thai trial (RV144) with a canarypox vector prime and protein boost, attenuated poxvirus recombinants expressing HIV-1 antigens are increasingly sought as vaccine candidates against HIV/AIDS. Here we describe using systems analysis the biological and immu...

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Bibliographic Details
Main Authors: Gómez, Carmen Elena, Perdiguero, Beatriz, Jiménez, Victoria, Filali-Mouhim, Abdelali, Ghneim, Khader, Haddad, Elias K., Quakkerlaar, Esther D., Delaloye, Julie, Harari, Alexandre, Roger, Thierry, Dunhen, Thomas, Sékaly, Rafick P., Melief, Cornelis J. M., Calandra, Thierry, Sallusto, Federica, Lanzavecchia, Antonio, Wagner, Ralf, Pantaleo, Giuseppe, Esteban, Mariano
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334902/