Endothelial Cell HIF-1α and HIF-2α Differentially Regulate Metastatic Success

Endothelial Cell HIF-1α and HIF-2α Differentially Regulate Metastatic Success

The hypoxia inducible transcription factors (HIFs) control many mediators of vascular response, including both angiogenic factors and small molecules such as nitric oxide (NO). In studying how endothelial HIF response itself affects metastasis, we found that loss of HIF-1α in endothelial cells reduc...

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Bibliographic Details
Main Authors: Branco-Price, Cristina, Zhang, Na, Schnelle, Moritz, Evans, Colin, Katschinski, Dörthe M., Liao, Debbie, Ellies, Lesley, Johnson, Randall S.
Format: Online
Language:English
Published: Cell Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334270/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334270/

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