Persisting Viral Sequences Shape Microbial CRISPR-based Immunity

Well-studied innate immune systems exist throughout bacteria and archaea, but a more recently discovered genomic locus may offer prokaryotes surprising immunological adaptability. Mediated by a cassette-like genomic locus termed Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), the...

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Bibliographic Details
Main Authors: Weinberger, Ariel D., Sun, Christine L., PluciƄski, Mateusz M., Denef, Vincent J., Thomas, Brian C., Horvath, Philippe, Barrangou, Rodolphe, Gilmore, Michael S., Getz, Wayne M., Banfield, Jillian F.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330103/