Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs

Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs

Schizophrenia is a complex disorder caused by both genetic and environmental factors. Using 9,087 cases, 12,171 controls and 915,354 imputed SNPs from the Psychiatric GWA Consortium for schizophrenia (PGC-SCZ) we estimate that 23% (s.e. 1%) of variation in liability to schizophrenia is captured by S...

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Bibliographic Details
Main Authors: Lee, S Hong, DeCandia, Teresa R, Ripke, Stephan, Yang, Jian, Sullivan, Patrick F, Goddard, Michael E, Keller, Matthew C, Visscher, Peter M, Wray, Naomi R
Format: Online
Language:English
Published: 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327879/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327879/

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