ATR cooperates with CTC1 and STN1 to maintain telomeres and genome integrity in Arabidopsis

Telomeres protect chromosome ends from DNA damage. CTC1/STN1/TEN1 (CST), a core telomere-capping complex in plant and vertebrates, suppresses an ATR-dependent DNA damage response in Arabidopsis. Protracted ATR inactivation inhibits telomerase, hastening the onset of telomere dysfunction in CST mutan...

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Bibliographic Details
Main Authors: Boltz, Kara A., Leehy, Katherine, Song, Xiangyu, Nelson, Andrew D., Shippen, Dorothy E.
Format: Online
Language:English
Published: The American Society for Cell Biology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327312/