ABL1 regulates spindle orientation in adherent cells and mammalian skin

Despite the growing evidence for the regulated spindle orientation in mammals, a systematic approach for identifying the responsible genes in mammalian cells has not been established. Here we perform a kinase-targeting RNAi screen in HeLa cells and identify ABL1 as a novel regulator of spindle orien...

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Bibliographic Details
Main Authors: Matsumura, Shigeru, Hamasaki, Mayumi, Yamamoto, Takuya, Ebisuya, Miki, Sato, Mizuho, Nishida, Eisuke, Toyoshima, Fumiko
Format: Online
Language:English
Published: Nature Pub. Group 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324324/