Epidemiologic Clues to SARS Origin in China
An epidemic of severe acute respiratory syndrome (SARS) began in Foshan municipality, Guangdong Province, China, in November 2002. We studied SARS case reports through April 30, 2003, including data from case investigations and a case series analysis of index cases. A total of 1,454 clinically confi...
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Centers for Disease Control and Prevention
2004
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323155/ |
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pubmed-33231552012-04-17 Epidemiologic Clues to SARS Origin in China Xu, Rui-Heng He, Jian-Feng Evans, Meirion R. Peng, Guo-Wen Field, Hume E Yu, De-Wen Lee, Chin-Kei Luo, Hui-Min Lin, Wei-Sheng Lin, Peng Li, Ling-Hui Liang, Wen-Jia Lin, Jin-Yan Schnur, Alan Research An epidemic of severe acute respiratory syndrome (SARS) began in Foshan municipality, Guangdong Province, China, in November 2002. We studied SARS case reports through April 30, 2003, including data from case investigations and a case series analysis of index cases. A total of 1,454 clinically confirmed cases (and 55 deaths) occurred; the epidemic peak was in the first week of February 2003. Healthcare workers accounted for 24% of cases. Clinical signs and symptoms differed between children (<18 years) and older persons (>65 years). Several observations support the hypothesis of a wild animal origin for SARS. Cases apparently occurred independently in at least five different municipalities; early case-patients were more likely than later patients to report living near a produce market (odds ratio undefined; lower 95% confidence interval 2.39) but not near a farm; and 9 (39%) of 23 early patients, including 6 who lived or worked in Foshan, were food handlers with probable animal contact. Centers for Disease Control and Prevention 2004-06 /pmc/articles/PMC3323155/ /pubmed/15207054 http://dx.doi.org/10.3201/eid1006.030852 Text en |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
Xu, Rui-Heng He, Jian-Feng Evans, Meirion R. Peng, Guo-Wen Field, Hume E Yu, De-Wen Lee, Chin-Kei Luo, Hui-Min Lin, Wei-Sheng Lin, Peng Li, Ling-Hui Liang, Wen-Jia Lin, Jin-Yan Schnur, Alan |
spellingShingle |
Xu, Rui-Heng He, Jian-Feng Evans, Meirion R. Peng, Guo-Wen Field, Hume E Yu, De-Wen Lee, Chin-Kei Luo, Hui-Min Lin, Wei-Sheng Lin, Peng Li, Ling-Hui Liang, Wen-Jia Lin, Jin-Yan Schnur, Alan Epidemiologic Clues to SARS Origin in China |
author_facet |
Xu, Rui-Heng He, Jian-Feng Evans, Meirion R. Peng, Guo-Wen Field, Hume E Yu, De-Wen Lee, Chin-Kei Luo, Hui-Min Lin, Wei-Sheng Lin, Peng Li, Ling-Hui Liang, Wen-Jia Lin, Jin-Yan Schnur, Alan |
author_sort |
Xu, Rui-Heng |
title |
Epidemiologic Clues to SARS Origin in China |
title_short |
Epidemiologic Clues to SARS Origin in China |
title_full |
Epidemiologic Clues to SARS Origin in China |
title_fullStr |
Epidemiologic Clues to SARS Origin in China |
title_full_unstemmed |
Epidemiologic Clues to SARS Origin in China |
title_sort |
epidemiologic clues to sars origin in china |
description |
An epidemic of severe acute respiratory syndrome (SARS) began in Foshan municipality, Guangdong Province, China, in November 2002. We studied SARS case reports through April 30, 2003, including data from case investigations and a case series analysis of index cases. A total of 1,454 clinically confirmed cases (and 55 deaths) occurred; the epidemic peak was in the first week of February 2003. Healthcare workers accounted for 24% of cases. Clinical signs and symptoms differed between children (<18 years) and older persons (>65 years). Several observations support the hypothesis of a wild animal origin for SARS. Cases apparently occurred independently in at least five different municipalities; early case-patients were more likely than later patients to report living near a produce market (odds ratio undefined; lower 95% confidence interval 2.39) but not near a farm; and 9 (39%) of 23 early patients, including 6 who lived or worked in Foshan, were food handlers with probable animal contact. |
publisher |
Centers for Disease Control and Prevention |
publishDate |
2004 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323155/ |
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1611520001358954496 |