Epidemiologic Clues to SARS Origin in China

An epidemic of severe acute respiratory syndrome (SARS) began in Foshan municipality, Guangdong Province, China, in November 2002. We studied SARS case reports through April 30, 2003, including data from case investigations and a case series analysis of index cases. A total of 1,454 clinically confi...

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Main Authors: Xu, Rui-Heng, He, Jian-Feng, Evans, Meirion R., Peng, Guo-Wen, Field, Hume E, Yu, De-Wen, Lee, Chin-Kei, Luo, Hui-Min, Lin, Wei-Sheng, Lin, Peng, Li, Ling-Hui, Liang, Wen-Jia, Lin, Jin-Yan, Schnur, Alan
Format: Online
Language:English
Published: Centers for Disease Control and Prevention 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323155/
id pubmed-3323155
recordtype oai_dc
spelling pubmed-33231552012-04-17 Epidemiologic Clues to SARS Origin in China Xu, Rui-Heng He, Jian-Feng Evans, Meirion R. Peng, Guo-Wen Field, Hume E Yu, De-Wen Lee, Chin-Kei Luo, Hui-Min Lin, Wei-Sheng Lin, Peng Li, Ling-Hui Liang, Wen-Jia Lin, Jin-Yan Schnur, Alan Research An epidemic of severe acute respiratory syndrome (SARS) began in Foshan municipality, Guangdong Province, China, in November 2002. We studied SARS case reports through April 30, 2003, including data from case investigations and a case series analysis of index cases. A total of 1,454 clinically confirmed cases (and 55 deaths) occurred; the epidemic peak was in the first week of February 2003. Healthcare workers accounted for 24% of cases. Clinical signs and symptoms differed between children (<18 years) and older persons (>65 years). Several observations support the hypothesis of a wild animal origin for SARS. Cases apparently occurred independently in at least five different municipalities; early case-patients were more likely than later patients to report living near a produce market (odds ratio undefined; lower 95% confidence interval 2.39) but not near a farm; and 9 (39%) of 23 early patients, including 6 who lived or worked in Foshan, were food handlers with probable animal contact. Centers for Disease Control and Prevention 2004-06 /pmc/articles/PMC3323155/ /pubmed/15207054 http://dx.doi.org/10.3201/eid1006.030852 Text en
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Xu, Rui-Heng
He, Jian-Feng
Evans, Meirion R.
Peng, Guo-Wen
Field, Hume E
Yu, De-Wen
Lee, Chin-Kei
Luo, Hui-Min
Lin, Wei-Sheng
Lin, Peng
Li, Ling-Hui
Liang, Wen-Jia
Lin, Jin-Yan
Schnur, Alan
spellingShingle Xu, Rui-Heng
He, Jian-Feng
Evans, Meirion R.
Peng, Guo-Wen
Field, Hume E
Yu, De-Wen
Lee, Chin-Kei
Luo, Hui-Min
Lin, Wei-Sheng
Lin, Peng
Li, Ling-Hui
Liang, Wen-Jia
Lin, Jin-Yan
Schnur, Alan
Epidemiologic Clues to SARS Origin in China
author_facet Xu, Rui-Heng
He, Jian-Feng
Evans, Meirion R.
Peng, Guo-Wen
Field, Hume E
Yu, De-Wen
Lee, Chin-Kei
Luo, Hui-Min
Lin, Wei-Sheng
Lin, Peng
Li, Ling-Hui
Liang, Wen-Jia
Lin, Jin-Yan
Schnur, Alan
author_sort Xu, Rui-Heng
title Epidemiologic Clues to SARS Origin in China
title_short Epidemiologic Clues to SARS Origin in China
title_full Epidemiologic Clues to SARS Origin in China
title_fullStr Epidemiologic Clues to SARS Origin in China
title_full_unstemmed Epidemiologic Clues to SARS Origin in China
title_sort epidemiologic clues to sars origin in china
description An epidemic of severe acute respiratory syndrome (SARS) began in Foshan municipality, Guangdong Province, China, in November 2002. We studied SARS case reports through April 30, 2003, including data from case investigations and a case series analysis of index cases. A total of 1,454 clinically confirmed cases (and 55 deaths) occurred; the epidemic peak was in the first week of February 2003. Healthcare workers accounted for 24% of cases. Clinical signs and symptoms differed between children (<18 years) and older persons (>65 years). Several observations support the hypothesis of a wild animal origin for SARS. Cases apparently occurred independently in at least five different municipalities; early case-patients were more likely than later patients to report living near a produce market (odds ratio undefined; lower 95% confidence interval 2.39) but not near a farm; and 9 (39%) of 23 early patients, including 6 who lived or worked in Foshan, were food handlers with probable animal contact.
publisher Centers for Disease Control and Prevention
publishDate 2004
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323155/
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