Dopamine Pathology in Schizophrenia: Analysis of Total and Phosphorylated Tyrosine Hydroxylase in the Substantia Nigra
Introduction: Despite the importance of dopamine neurotransmission in schizophrenia, very few studies have addressed anomalies in the mesencephalic dopaminergic neurons of the substantia nigra/ventral tegmental area (SN/VTA). Tyrosine hydroxylase (TH) is the rate-limiting enzyme for the production o...
Main Authors: | , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Frontiers Research Foundation
2012
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321522/ |