A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis
Crystallographic structures encompassing GPCR autoproteolytic sequences (GPS) delineate a novel conserved structural domain called GAIN, which is found in cell-adhesion GPCRs, polycystic kidney disease proteins conserved throughout evolution.
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321182/ |