ORC1 BAH domain links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome

Recognition of distinctly modified histones by specialized “effector” proteins constitutes a key mechanism for transducing molecular events at chromatin to biological outcomes1. Effector proteins influence DNA-templated processes, including transcription, DNA recombination, and DNA repair; however,...

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Bibliographic Details
Main Authors: Kuo, Alex J., Song, Jikui, Cheung, Peggie, Ishibe-Murakami, Satoko, Yamazoe, Sayumi, Chen, James K., Patel, Dinshaw J., Gozani, Or
Format: Online
Language:English
Published: 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321094/