ORC1 BAH domain links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome
Recognition of distinctly modified histones by specialized “effector” proteins constitutes a key mechanism for transducing molecular events at chromatin to biological outcomes1. Effector proteins influence DNA-templated processes, including transcription, DNA recombination, and DNA repair; however,...
Main Authors: | , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
2012
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321094/ |