Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein

Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein

The conversion of chemical energy into mechanical force by AAA+ (ATPases associated with diverse cellular activities) ATPases is integral to cellular processes, including DNA replication, protein unfolding, cargo transport, and membrane fusion1. The AAA+ ATPase motor cytoplasmic dynein regulates cil...

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Bibliographic Details
Main Authors: Firestone, Ari J., Weinger, Joshua S., Maldonado, Maria, Barlan, Kari, Langston, Lance D., O'Donnell, Michael, Gelfand, Vladimir I., Kapoor, Tarun M., Chen, James K.
Format: Online
Language:English
Published: 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321072/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321072/

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