The Need for Continued Development of Ricin Countermeasures

Ricin toxin, an extremely potent and heat-stable toxin produced from the bean of the ubiquitous Ricinus communis (castor bean plant), has been categorized by the US Centers for Disease Control and Prevention (CDC) as a category B biothreat agent that is moderately easy to disseminate. Ricin has the...

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Main Authors: Reisler, Ronald B., Smith, Leonard A.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318197/
id pubmed-3318197
recordtype oai_dc
spelling pubmed-33181972012-04-25 The Need for Continued Development of Ricin Countermeasures Reisler, Ronald B. Smith, Leonard A. Review Article Ricin toxin, an extremely potent and heat-stable toxin produced from the bean of the ubiquitous Ricinus communis (castor bean plant), has been categorized by the US Centers for Disease Control and Prevention (CDC) as a category B biothreat agent that is moderately easy to disseminate. Ricin has the potential to be used as an agent of biological warfare and bioterrorism. Therefore, there is a critical need for continued development of ricin countermeasures. A safe and effective prophylactic vaccine against ricin that was FDA approved for “at risk” individuals would be an important first step in assuring the availability of medical countermeasures against ricin. Hindawi Publishing Corporation 2012 2012-03-26 /pmc/articles/PMC3318197/ /pubmed/22536516 http://dx.doi.org/10.1155/2012/149737 Text en Copyright © 2012 R. B. Reisler and L. A. Smith. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Reisler, Ronald B.
Smith, Leonard A.
spellingShingle Reisler, Ronald B.
Smith, Leonard A.
The Need for Continued Development of Ricin Countermeasures
author_facet Reisler, Ronald B.
Smith, Leonard A.
author_sort Reisler, Ronald B.
title The Need for Continued Development of Ricin Countermeasures
title_short The Need for Continued Development of Ricin Countermeasures
title_full The Need for Continued Development of Ricin Countermeasures
title_fullStr The Need for Continued Development of Ricin Countermeasures
title_full_unstemmed The Need for Continued Development of Ricin Countermeasures
title_sort need for continued development of ricin countermeasures
description Ricin toxin, an extremely potent and heat-stable toxin produced from the bean of the ubiquitous Ricinus communis (castor bean plant), has been categorized by the US Centers for Disease Control and Prevention (CDC) as a category B biothreat agent that is moderately easy to disseminate. Ricin has the potential to be used as an agent of biological warfare and bioterrorism. Therefore, there is a critical need for continued development of ricin countermeasures. A safe and effective prophylactic vaccine against ricin that was FDA approved for “at risk” individuals would be an important first step in assuring the availability of medical countermeasures against ricin.
publisher Hindawi Publishing Corporation
publishDate 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318197/
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