A Human PrM Antibody That Recognizes a Novel Cryptic Epitope on Dengue E Glycoprotein

Dengue virus (DENV) is a major mosquito-borne pathogen infecting up to 100 million people each year; so far no effective treatment or vaccines are available. Recently, highly cross-reactive and infection-enhancing pre-membrane (prM)-specific antibodies were found to dominate the anti-DENV immune res...

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Bibliographic Details
Main Authors: Chan, Annie Hoi Yi, Tan, Hwee Cheng, Chow, Angelia Yee, Lim, Angeline Pei Chiew, Lok, Shee Mei, Moreland, Nicole J., Vasudevan, Subhash G., MacAry, Paul A., Ooi, Eng Eong, Hanson, Brendon J.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317930/