Improved Mitochondrial Function with Diet-Induced Increase in Either Docosahexaenoic Acid or Arachidonic Acid in Membrane Phospholipids

Mitochondria can depolarize and trigger cell death through the opening of the mitochondrial permeability transition pore (MPTP). We recently showed that an increase in the long chain n3 polyunsaturated fatty acids (PUFA) docosahexaenoic acid (DHA; 22:6n3) and depletion of the n6 PUFA arachidonic aci...

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Bibliographic Details
Main Authors: Khairallah, Ramzi J., Kim, Junhwan, O'Shea, Karen M., O'Connell, Kelly A., Brown, Bethany H., Galvao, Tatiana, Daneault, Caroline, Rosiers, Christine Des, Polster, Brian M., Hoppel, Charles L., Stanley, William C.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316678/