“Point” Centromeres of Saccharomyces Harbor Single Centromere-Specific Nucleosomes

The “point” centromere of budding yeast is genetically defined by an ∼125-bp sequence. Recent fluorescence measurements of kinetochore clusters have suggested that this sequence specifies multiple centromere histone 3 (CenH3) nucleosomes. However, high-resolution mapping demonstrates that there is o...

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Bibliographic Details
Main Authors: Henikoff, Steven, Henikoff, Jorja G.
Format: Online
Language:English
Published: Genetics Society of America 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316665/