Compensatory T-Cell Regulation in Unaffected Relatives of SLE Patients, and Opposite IL-2/CD25-Mediated Effects Suggested by Coreferentiality Modeling

Compensatory T-Cell Regulation in Unaffected Relatives of SLE Patients, and Opposite IL-2/CD25-Mediated Effects Suggested by Coreferentiality Modeling

In human systemic lupus erythematosus (SLE), diverse autoantibodies accumulate over years before disease manifestation. Unaffected relatives of SLE patients frequently share a sustained production of autoantibodies with indiscriminable specificity, usually without ever acquiring the disease. We stud...

Full description

Bibliographic Details
Main Authors: Fesel, Constantin, Barreto, Marta, Ferreira, Ricardo C., Costa, Nuno, Venda, Lara L., Pereira, Clara, Carvalho, Claudia, Morães-Fontes, Maria Francisca, Ferreira, Carlos M., Vasconcelos, Carlos, Viana, João F., Santos, Eugenia, Martins, Berta, Demengeot, Jocelyne, Vicente, Astrid M.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315511/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315511/

Similar Items