A Cell Permeable Peptide Inhibitor of NFAT Inhibits Macrophage Cytokine Expression and Ameliorates Experimental Colitis

Nuclear factor of activated T cells (NFAT) plays a critical role in the development and function of immune and non-immune cells. Although NFAT is a central transcriptional regulator of T cell cytokines, its role in macrophage specific gene expression is less defined. Previous work from our group dem...

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Bibliographic Details
Main Authors: Elloumi, Houda Z., Maharshak, Nitsan, Rao, Kavitha N., Kobayashi, Taku, Ryu, Hyungjin S., Mühlbauer, Marcus, Li, Fengling, Jobin, Christian, Plevy, Scott E.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313977/