A Pilot Study on Developing Mucosal Vaccine against Alveolar Echinococcosis (AE) Using Recombinant Tetraspanin 3: Vaccine Efficacy and Immunology

Humans and rodents become infected with E. multilocularis by oral ingesting of the eggs, which then develop into cysts in the liver and progress an endless proliferation. Untreated AE has a fatality rate of >90% in humans. Tetraspanins have been identified in Schistosoma and showed potential as t...

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Bibliographic Details
Main Authors: Dang, Zhisheng, Yagi, Kinpei, Oku, Yuzaburo, Kouguchi, Hirokazu, Kajino, Kiichi, Matsumoto, Jun, Nakao, Ryo, Wakaguri, Hiroyuki, Toyoda, Atsushi, Yin, Hong, Sugimoto, Chihiro
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313938/