parkin-induced defects in neurophysiology and locomotion are generated by metabolic dysfunction and not oxidative stress
Parkinson's disease (PD) is characterized by movement disorders, including bradykinesia. Analysis of inherited, juvenile PD, identified several genes linked via a common pathway to mitochondrial dysfunction. In this study, we demonstrate that the larva of the Drosophila parkin mutant faithfully...
Main Authors: | , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313793/ |