Transforming the Untransformable: Application of Direct Transformation To Manipulate Genetically Staphylococcus aureus and Staphylococcus epidermidis

The strong restriction barrier present in Staphylococcus aureus and Staphylococcus epidermidis has limited functional genomic analysis to a small subset of strains that are amenable to genetic manipulation. Recently, a conserved type IV restriction system termed SauUSI (which specifically recognizes...

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Bibliographic Details
Main Authors: Monk, Ian R., Shah, Ishita M., Xu, Min, Tan, Man-Wah, Foster, Timothy J.
Format: Online
Language:English
Published: American Society of Microbiology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312211/