Increased Gut Permeability and Microbiota Change Associate with Mesenteric Fat Inflammation and Metabolic Dysfunction in Diet-Induced Obese Mice

We investigated the relationship between gut health, visceral fat dysfunction and metabolic disorders in diet-induced obesity. C57BL/6J mice were fed control or high saturated fat diet (HFD). Circulating glucose, insulin and inflammatory markers were measured. Proximal colon barrier function was ass...

Full description

Bibliographic Details
Main Authors: Lam, Yan Y., Ha, Connie W. Y., Campbell, Craig R., Mitchell, Andrew J., Dinudom, Anuwat, Oscarsson, Jan, Cook, David I., Hunt, Nicholas H., Caterson, Ian D., Holmes, Andrew J., Storlien, Len H.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311621/