L(+) and D(−) Lactate Are Increased in Plasma and Urine Samples of Type 2 Diabetes as Measured by a Simultaneous Quantification of L(+) and D(−) Lactate by Reversed-Phase Liquid Chromatography Tandem Mass Spectrometry

Background. Plasma and urinary levels of D-lactate have been linked to the presence of diabetes. Previously developed techniques have shown several limitations to further evaluate D-lactate as a biomarker for this condition. Methods. D- and L-lactate were quantified using ultraperformance liquid ch...

Full description

Bibliographic Details
Main Authors: Scheijen, Jean L. J. M., Hanssen, Nordin M. J., van de Waarenburg, Marjo P. H., Jonkers, Daisy M. A. E., Stehouwer, Coen D. A., Schalkwijk, Casper G.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310144/