Flexible antibodies with nonprotein hinges
There is a significant need for antibodies that can bind targets with greater affinity. Here we describe a novel strategy employing chemical semisynthesis to produce symmetroadhesins: antibody-like molecules having nonprotein hinge regions that are more flexible and extendible and are capable of two...
| Main Authors: | , , , , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Japan Academy
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309923/ |