Predicting the Clinical Outcome of Severe Falciparum Malaria in African Children: Findings From a Large Randomized Trial
Four predictors were independently associated with an increased risk of death: acidosis, cerebral manifestations of malaria, elevated blood urea nitrogen, or signs of chronic illness. The standard base deficit was found to be the single most relevant predictor of death.
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| Format: | Online |
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Oxford University Press
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309889/ |
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pubmed-3309889 |
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pubmed-33098892012-04-15 Predicting the Clinical Outcome of Severe Falciparum Malaria in African Children: Findings From a Large Randomized Trial von Seidlein, Lorenz Olaosebikan, Rasaq Hendriksen, Ilse C. E. Lee, Sue J. Adedoyin, Olanrewaju Timothy Agbenyega, Tsiri Nguah, Samuel Blay Bojang, Kalifa Deen, Jacqueline L. Evans, Jennifer Fanello, Caterina I. Gomes, Ermelinda Pedro, Alínia José Kahabuka, Catherine Karema, Corine Kivaya, Esther Maitland, Kathryn Mokuolu, Olugbenga A. Mtove, George Mwanga-Amumpaire, Juliet Nadjm, Behzad Nansumba, Margaret Ngum, Wirichada Pan Onyamboko, Marie A. Reyburn, Hugh Sakulthaew, Tharisara Silamut, Kamolrat Tshefu, Antoinette K. Umulisa, Noella Gesase, Samwel Day, Nicholas P. J. White, Nicholas J. Dondorp, Arjen M. Articles and Commentaries Four predictors were independently associated with an increased risk of death: acidosis, cerebral manifestations of malaria, elevated blood urea nitrogen, or signs of chronic illness. The standard base deficit was found to be the single most relevant predictor of death. Oxford University Press 2012-04-15 /pmc/articles/PMC3309889/ /pubmed/22412067 http://dx.doi.org/10.1093/cid/cis034 Text en © The Author 2012. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please email:journals.permissions@oup.com. http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
von Seidlein, Lorenz Olaosebikan, Rasaq Hendriksen, Ilse C. E. Lee, Sue J. Adedoyin, Olanrewaju Timothy Agbenyega, Tsiri Nguah, Samuel Blay Bojang, Kalifa Deen, Jacqueline L. Evans, Jennifer Fanello, Caterina I. Gomes, Ermelinda Pedro, Alínia José Kahabuka, Catherine Karema, Corine Kivaya, Esther Maitland, Kathryn Mokuolu, Olugbenga A. Mtove, George Mwanga-Amumpaire, Juliet Nadjm, Behzad Nansumba, Margaret Ngum, Wirichada Pan Onyamboko, Marie A. Reyburn, Hugh Sakulthaew, Tharisara Silamut, Kamolrat Tshefu, Antoinette K. Umulisa, Noella Gesase, Samwel Day, Nicholas P. J. White, Nicholas J. Dondorp, Arjen M. |
| spellingShingle |
von Seidlein, Lorenz Olaosebikan, Rasaq Hendriksen, Ilse C. E. Lee, Sue J. Adedoyin, Olanrewaju Timothy Agbenyega, Tsiri Nguah, Samuel Blay Bojang, Kalifa Deen, Jacqueline L. Evans, Jennifer Fanello, Caterina I. Gomes, Ermelinda Pedro, Alínia José Kahabuka, Catherine Karema, Corine Kivaya, Esther Maitland, Kathryn Mokuolu, Olugbenga A. Mtove, George Mwanga-Amumpaire, Juliet Nadjm, Behzad Nansumba, Margaret Ngum, Wirichada Pan Onyamboko, Marie A. Reyburn, Hugh Sakulthaew, Tharisara Silamut, Kamolrat Tshefu, Antoinette K. Umulisa, Noella Gesase, Samwel Day, Nicholas P. J. White, Nicholas J. Dondorp, Arjen M. Predicting the Clinical Outcome of Severe Falciparum Malaria in African Children: Findings From a Large Randomized Trial |
| author_facet |
von Seidlein, Lorenz Olaosebikan, Rasaq Hendriksen, Ilse C. E. Lee, Sue J. Adedoyin, Olanrewaju Timothy Agbenyega, Tsiri Nguah, Samuel Blay Bojang, Kalifa Deen, Jacqueline L. Evans, Jennifer Fanello, Caterina I. Gomes, Ermelinda Pedro, Alínia José Kahabuka, Catherine Karema, Corine Kivaya, Esther Maitland, Kathryn Mokuolu, Olugbenga A. Mtove, George Mwanga-Amumpaire, Juliet Nadjm, Behzad Nansumba, Margaret Ngum, Wirichada Pan Onyamboko, Marie A. Reyburn, Hugh Sakulthaew, Tharisara Silamut, Kamolrat Tshefu, Antoinette K. Umulisa, Noella Gesase, Samwel Day, Nicholas P. J. White, Nicholas J. Dondorp, Arjen M. |
| author_sort |
von Seidlein, Lorenz |
| title |
Predicting the Clinical Outcome of Severe Falciparum Malaria in African Children: Findings From a Large Randomized Trial |
| title_short |
Predicting the Clinical Outcome of Severe Falciparum Malaria in African Children: Findings From a Large Randomized Trial |
| title_full |
Predicting the Clinical Outcome of Severe Falciparum Malaria in African Children: Findings From a Large Randomized Trial |
| title_fullStr |
Predicting the Clinical Outcome of Severe Falciparum Malaria in African Children: Findings From a Large Randomized Trial |
| title_full_unstemmed |
Predicting the Clinical Outcome of Severe Falciparum Malaria in African Children: Findings From a Large Randomized Trial |
| title_sort |
predicting the clinical outcome of severe falciparum malaria in african children: findings from a large randomized trial |
| description |
Four predictors were independently associated with an increased risk of death: acidosis, cerebral manifestations of malaria, elevated blood urea nitrogen, or signs of chronic illness. The standard base deficit was found to be the single most relevant predictor of death. |
| publisher |
Oxford University Press |
| publishDate |
2012 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309889/ |
| _version_ |
1611515996129984512 |