Diverse Roles of JNK and MKK Pathways in the Brain

The c-Jun NH2-terminal protein kinase (JNK) plays important roles in a broad range of physiological processes. JNK is controlled by two upstream regulators, mitogen-activated protein kinase kinase (MKK) 4 and MKK7, which are activated by various MAPKKKs. Studies employing knockout mice have demonstr...

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Bibliographic Details
Main Authors: Yamasaki, Tokiwa, Kawasaki, Hiroshi, Nishina, Hiroshi
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307000/