Both FA- and mPEG-conjugated chitosan nanoparticles for targeted cellular uptake and enhanced tumor tissue distribution

Both folic acid (FA)- and methoxypoly(ethylene glycol) (mPEG)-conjugated chitosan nanoparticles (NPs) had been designed for targeted and prolong anticancer drug delivery system. The chitosan NPs were prepared with combination of ionic gelation and chemical cross-linking method, followed by conjugati...

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Bibliographic Details
Main Authors: Hou, Zhenqing, Zhan, Chuanming, Jiang, Qiwei, Hu, Quan, Li, Le, Chang, Di, Yang, Xiangrui, Wang, Yixiao, Li, Yang, Ye, Shefang, Xie, Liya, Yi, Yunfeng, Zhang, Qiqing
Format: Online
Language:English
Published: Springer 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306018/