HMOX1 Gene Promoter Alleles and High HO-1 Levels Are Associated with Severe Malaria in Gambian Children

HMOX1 Gene Promoter Alleles and High HO-1 Levels Are Associated with Severe Malaria in Gambian Children

Heme oxygenase 1 (HO-1) is an essential enzyme induced by heme and multiple stimuli associated with critical illness. In humans, polymorphisms in the HMOX1 gene promoter may influence the magnitude of HO-1 expression. In many diseases including murine malaria, HO-1 induction produces protective anti...

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Bibliographic Details
Main Authors: Walther, Michael, De Caul, Adam, Aka, Peter, Njie, Madi, Amambua-Ngwa, Alfred, Walther, Brigitte, Predazzi, Irene M., Cunnington, Aubrey, Deininger, Susanne, Takem, Ebako N., Ebonyi, Augustine, Weis, Sebastian, Walton, Robert, Rowland-Jones, Sarah, Sirugo, Giorgio, Williams, Scott M., Conway, David J.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305414/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305414/

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