Neurobeachin, a Regulator of Synaptic Protein Targeting, Is Associated with Body Fat Mass and Feeding Behavior in Mice and Body-Mass Index in Humans

Neurobeachin, a Regulator of Synaptic Protein Targeting, Is Associated with Body Fat Mass and Feeding Behavior in Mice and Body-Mass Index in Humans

Neurobeachin (Nbea) regulates neuronal membrane protein trafficking and is required for the development and functioning of central and neuromuscular synapses. In homozygous knockout (KO) mice, Nbea deficiency causes perinatal death. Here, we report that heterozygous KO mice haploinsufficient for Nbe...

Full description

Bibliographic Details
Main Authors: Olszewski, Pawel K., Rozman, Jan, Jacobsson, Josefin A., Rathkolb, Birgit, Strömberg, Siv, Hans, Wolfgang, Klockars, Anica, Alsiö, Johan, Risérus, Ulf, Becker, Lore, Hölter, Sabine M., Elvert, Ralf, Ehrhardt, Nicole, Gailus-Durner, Valérie, Fuchs, Helmut, Fredriksson, Robert, Wolf, Eckhard, Klopstock, Thomas, Wurst, Wolfgang, Levine, Allen S., Marcus, Claude, Hrabě de Angelis, Martin, Klingenspor, Martin, Schiöth, Helgi B., Kilimann, Manfred W.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305408/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305408/

Similar Items