Oral lichen planus - Review on etiopathogenesis
Oral lichen planus (OLP) is a chronic mucocutaneous disease of uncertain etiopathogenesis. Several factors including stress, genetics, systemic diseases, viruses, dental restorative materials and drugs have been implicated as causative agents. The disease seems to be mediated by an antigen specific...
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| Format: | Online |
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Medknow Publications
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304232/ |
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pubmed-33042322012-03-22 Oral lichen planus - Review on etiopathogenesis Srinivas, K. Aravinda, K. Ratnakar, P. Nigam, Nitin Gupta, Siddharth Review Article Oral lichen planus (OLP) is a chronic mucocutaneous disease of uncertain etiopathogenesis. Several factors including stress, genetics, systemic diseases, viruses, dental restorative materials and drugs have been implicated as causative agents. The disease seems to be mediated by an antigen specific mechanism, activating cytotoxic T cells, and non specific mechanisms like mast cell degranulation and matrix metalloproteinase activation. Further clarity on the pathogenesis will aid in modifying therapeutic interventions, thus significantly reducing the morbidity of OLP patients. Medknow Publications 2011 /pmc/articles/PMC3304232/ /pubmed/22442603 http://dx.doi.org/10.4103/0975-5950.85847 Text en Copyright: © National Journal of Maxillofacial Surgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Srinivas, K. Aravinda, K. Ratnakar, P. Nigam, Nitin Gupta, Siddharth |
| spellingShingle |
Srinivas, K. Aravinda, K. Ratnakar, P. Nigam, Nitin Gupta, Siddharth Oral lichen planus - Review on etiopathogenesis |
| author_facet |
Srinivas, K. Aravinda, K. Ratnakar, P. Nigam, Nitin Gupta, Siddharth |
| author_sort |
Srinivas, K. |
| title |
Oral lichen planus - Review on etiopathogenesis |
| title_short |
Oral lichen planus - Review on etiopathogenesis |
| title_full |
Oral lichen planus - Review on etiopathogenesis |
| title_fullStr |
Oral lichen planus - Review on etiopathogenesis |
| title_full_unstemmed |
Oral lichen planus - Review on etiopathogenesis |
| title_sort |
oral lichen planus - review on etiopathogenesis |
| description |
Oral lichen planus (OLP) is a chronic mucocutaneous disease of uncertain etiopathogenesis. Several factors including stress, genetics, systemic diseases, viruses, dental restorative materials and drugs have been implicated as causative agents. The disease seems to be mediated by an antigen specific mechanism, activating cytotoxic T cells, and non specific mechanisms like mast cell degranulation and matrix metalloproteinase activation. Further clarity on the pathogenesis will aid in modifying therapeutic interventions, thus significantly reducing the morbidity of OLP patients. |
| publisher |
Medknow Publications |
| publishDate |
2011 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304232/ |
| _version_ |
1611514158566604800 |