Nevirapine-Based Antiretroviral Therapy Impacts Artesunate and Dihydroartemisinin Disposition in HIV-Infected Nigerian Adults

Background. Nevirapine- (NVP-) based antiretroviral therapy (ART) and artesunate-amodiaquine are frequently coprescribed in areas of HIV and malaria endemicity. We explored the impact of this practice on artesunate and dihydroartemisinin pharmacokinetics. Methods. We conducted a parallel-group phar...

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Bibliographic Details
Main Authors: Fehintola, Fatai A., Scarsi, Kimberly K., Ma, Qing, Parikh, Sunil, Morse, Gene D., Taiwo, Babafemi, Akinola, Ibrahim Tope, Adewole, Isaac F., Lindegardh, Niklas, Phakderaj, Aphiradee, Ojengbede, Oladosu, Murphy, Robert L., Akinyinka, Olusegun O., Aweeka, Francesca T.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303559/