Uncovering the Molecular Machinery of the Human Spindle—An Integration of Wet and Dry Systems Biology

The mitotic spindle is an essential molecular machine involved in cell division, whose composition has been studied extensively by detailed cellular biology, high-throughput proteomics, and RNA interference experiments. However, because of its dynamic organization and complex regulation it is diffic...

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Bibliographic Details
Main Authors: Rojas, Ana M., Santamaria, Anna, Malik, Rainer, Jensen, Thomas Skøt, Körner, Roman, Morilla, Ian, de Juan, David, Krallinger, Martin, Hansen, Daniel Aaen, Hoffmann, Robert, Lees, Jonathan, Reid, Adam, Yeats, Corin, Wehner, Anja, Elowe, Sabine, Clegg, Andrew B., Brunak, Søren, Nigg, Erich A., Orengo, Christine, Valencia, Alfonso, Ranea, Juan A. G.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302876/