Non-Enzymatic Decomposition of Collagen Fibers by a Biglycan Antibody and a Plausible Mechanism for Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a systemic autoimmune inflammatory and destructive joint disorder that affects tens of millions of people worldwide. Normal healthy joints maintain a balance between the synthesis of extracellular matrix (ECM) molecules and the proteolytic degradation of damaged ones. In...
Main Authors: | , |
---|---|
Format: | Online |
Language: | English |
Published: |
Public Library of Science
2012
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302792/ |