GPI-anchor synthesis is indispensable for the germline development of the nematode Caenorhabditis elegans
Twenty-four Caenorhabditis elegans genes are involved in GPI-anchor synthesis. Based on the isolation of a deletion allele of the PIGA gene mediating the first step of GPI-anchor synthesis, GPI-anchor synthesis in somatic gonads and/or in germline is shown to be indispensable for the normal developm...
Main Authors: | , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The American Society for Cell Biology
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302757/ |