GPI-anchor synthesis is indispensable for the germline development of the nematode Caenorhabditis elegans

Twenty-four Caenorhabditis elegans genes are involved in GPI-anchor synthesis. Based on the isolation of a deletion allele of the PIGA gene mediating the first step of GPI-anchor synthesis, GPI-anchor synthesis in somatic gonads and/or in germline is shown to be indispensable for the normal developm...

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Main Authors: Murata, Daisuke, Nomura, Kazuko H., Dejima, Katsufumi, Mizuguchi, Souhei, Kawasaki, Nana, Matsuishi-Nakajima, Yukari, Ito, Satsuki, Gengyo-Ando, Keiko, Kage-Nakadai, Eriko, Mitani, Shohei, Nomura, Kazuya
Format: Online
Language:English
Published: The American Society for Cell Biology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302757/