Protection against SHIV-KB9 Infection by Combining rDNA and rFPV Vaccines Based on HIV Multiepitope and p24 Protein in Chinese Rhesus Macaques

Developing an effective vaccine against HIV infection remains an urgent goal. We used a DNA prime/fowlpox virus boost regimen to immunize Chinese rhesus macaques. The animals were challenged intramuscularly with pathogenic molecularly cloned SHIV-KB9. Immunogenicity and protective efficacy of vaccin...

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Bibliographic Details
Main Authors: Li, Chang, Shen, Zhenwei, Li, Xiao, Bai, Jieying, Zeng, Lin, Tian, Mingyao, Song, Ying Jin, Ye, Ming, Du, Shouwen, Ren, Dayong, Liu, Cunxia, Zhu, Na, Sun, Dandan, Li, Yi, Jin, Ningyi
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299295/