STITCHER: Dynamic assembly of likely amyloid and prion β-structures from secondary structure predictions

The supersecondary structure of amyloids and prions, proteins of intense clinical and biological interest, are difficult to determine by standard experimental or computational means. In addition, significant conformational heterogeneity is known or suspected to exist in many amyloid fibrils. Previou...

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Bibliographic Details
Main Authors: Bryan, Allen W, O’Donnell, Charles W, Menke, Matthew, Cowen, Lenore J, Lindquist, Susan, Berger, Bonnie
Format: Online
Language:English
Published: Wiley Subscription Services, Inc., A Wiley Company 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298606/