Forebrain glutamatergic neurons mediate leptin action on depression-like behaviors and synaptic depression

The glutamatergic system has been implicated in the pathophysiology of depression and the mechanism of action of antidepressants. Leptin, an adipocyte-derived hormone, has antidepressant-like properties. However, the functional role of leptin receptor (Lepr) signaling in glutamatergic neurons remain...

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Bibliographic Details
Main Authors: Guo, M, Lu, Y, Garza, J C, Li, Y, Chua, S C, Zhang, W, Lu, B, Lu, X-Y
Format: Online
Language:English
Published: Nature Publishing Group 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298113/