The Effect of Chaperonin Buffering on Protein Evolution
Molecular chaperones are highly conserved and ubiquitous proteins that help other proteins in the cell to fold. Pioneering work by Rutherford and Lindquist suggested that the chaperone Hsp90 could buffer (i.e., suppress) phenotypic variation in its client proteins and that alternate periods of buffe...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Oxford University Press
2010
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296372/ |