Bistability in feedback circuits as a byproduct of evolution of evolvability
Simulations of the evolution of simple gene regulatory networks reveal that fluctuating environmental selection can lead to the emergence of bistability under certain conditions where fluctuation and mutational rates are in tune.
Main Authors: | , |
---|---|
Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2012
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296359/ |