Selection of recombinant MVA by rescue of the essential D4R gene
Modified vaccinia virus Ankara (MVA) has become a promising vaccine vector due to its immunogenicity and its proven safety in humans. As a general approach for stringent and rapid selection of recombinant MVA, we assessed marker rescue of the essential viral D4R gene in an engineered deletion mutant...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293099/ |