Curtailing side effects in chemotherapy: a tale of PKCδ in cisplatin treatment

The efficacy of chemotherapy is often limited by side effects in normal tissues. This is exemplified by cisplatin, a widely used anti-cancer drug that may induce serious toxicity in normal tissues and organs including the kidneys. Decades of research have delineated multiple signaling pathways that...

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Bibliographic Details
Main Authors: Pabla, Navjotsingh, Dong, Zheng
Format: Online
Language:English
Published: Impact Journals LLC 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292897/