In Vitro Assessment of Cytochrome P450 2C19 Potential of Naoxintong

The effects of Buchang Naoxintong Capsules (BNCs) on S-mephenytoin 4′-hydroxylation activities in human liver microsomes in vitro were assessed. Human liver microsome was prepared by different ultracentrifugation. Human liver microsome incubation experiment was carried out to assay BNC on S-mephenyt...

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Bibliographic Details
Main Authors: Chen, Hui, Zhang, Ya, Wu, Xiaoying, Li, Candong, Wang, Huan
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292222/